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Therefore, these two above diseases may interplay with each other and even promote each other

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For the treatment of malignant tumors, a number of therapeutic mAbs targeting IGF-1R have been developed, including ganitumab (IgG1) (139), cixutumumab (IgG1) (221223), and figitumumab (IgG2) (222, 224, 225)

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Serum phosphorus levels should be regularly monitored and appropriate amounts of phosphorus should be added to the infusions to maintain normal serum phosphorus levels